Monday, January 7, 2008

What is the pharmacokinetic of Transamin after administration?

Pharmacokinetic parameters of Transamin after oral administration or injection are follows :

Tranexamic acid is rapidly absorbed when orally administered to healthy adult volunteers in a single dose of 250 or 500 mg, intramuscularly administered in a dose of 500 mg, or intravenously administered in a dose of 1,000 mg. Approximately 40 to 70% (when orally administered in a dose of 250 or 500 mg) or 80% and 76% (when intramuscularly administered in a dose of 500 mg and intravenously administered in a dose of 1,000 mg) respectively) of the drug are excreted into urine as unchanged compounds within 24 hours after administration.

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