Monday, January 7, 2008

What is DIC?

DIC stands for disseminated intravascular coagulation syndrome or diffuse intravascular coagulation syndrome. It is a sign of bleeding susequent to unadjustable activation of coagulatio factors and fibrinolytic enzymes in small vessels. When DIC occurs, fibrin deposits, and fibrinogen, prothrombin, coagulation factors (Factors V, VIII, XIII), and platelets are consumed in the process of coagulation. Fibrin degradatin products inhibit polumerization of fibrin, which results in tissue necrosis and bleeding.

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