Monday, January 7, 2008

How Transamin has the hemostatic effect?

Tranexamic acid firmly binds to the lysine binding site (LBS), which is the fibrin affinity site of plasmin or plasminogen, and prevents access of plasmin or plasminogen to the fibrin molecule. Therefore, degradation of fibrin by plasmin is strongly inhibited. Tranexamic acid is considered to stop bleeding by blocking the degradation of fibrin.

No comments: